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Molzym's Molecular Diagnostic Solutions
mNGS 為什麼 要使用Molzym
全自動病原菌DNA萃取設備與試劑前處理

病原菌DNA純度最高
病人的檢體中,一定會有人類DNA,這會干擾後續的PCR或定序判讀。所以我們的設備操作多了一個除去人類DNA的步驟,可以保證除去99%的干擾,取得純度最高的病原菌DNA

節省人力
不同於傳統culturing,操作人員使用全自動設備能最低限度的接觸到病原體,每次上機時間約2小時,實際hands-on的時間只有0.5hr, 每次上機一個run可放12個samples,一個人力一天可跑3個runs。

不到一天就可出報告
採用全自動設備將為您的實驗室幫上很大的忙。由自動化設備萃取出的DNA可直接上PCR,PCR一般需要2hr,就可知道+/-結果,然後再送定序,通常5hr就可拿到定序結果,我們會教您如何BLAST,使用我們設備的客戶已經可以快速的判斷1300種病原菌
適用多種檢體,四個步驟出報告

訂購資訊
品名
產品敘述
型號
SelectNA™plus
Instrument for automated pathogen DNA extraction
D-400-001
MolYsis-SelectNA™plus
(此為RUO版)
Kit for fully automated enrichment and isolation of microbial DNA, 48 reactions
for research use
適用檢體類型:
D-450-048
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EDTA blood
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Bronchoalveolar lavage
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Ascites fluid
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Joint aspirates
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CSF
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Swabs
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Sonicate fluids
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Various tissue biopsies
Micro-Dx™
(此為IVD版)
Kit for fully automated enrichment and isolation of microbial DNA, 48 reactions
for in-vitro diagnosis
適用檢體類型: 同上
U-200-048
廠牌: Molzym 產地: 德國


D-400-001
U-200-048
參考文獻
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Marbjerg LH, Holzknecht BJ, Dargis R, Dessau RB, Nielsen XHC, Christensen JJ (2020) Commercial bacterial and fungal broad-range PCR (Micro-Dx™) used on culture-negative specimens from normally sterile sites: diagnostic value and implications for antimicrobial treatment. Diagn Microbiol Infect Dis. 2020 Feb 22:115028. https://doi.org/10.1016/j.diagmicrobio.2020.115028
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Lustig M (2018) Clinical evaluation of Micro-Dx™ CE IVD – eubacterial and panfungal PCR diagnosis using automated DNA extraction. Trends in Molecular Diagnostics, no. 1/18: 1-2 (Molzym application note).
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Rubalskii E, Ruemke S, Salmoukas C, Baussmerth C, Keim S, Linow M, Disqué C, Haverich A, Kühn C (2018) Broad-range 16S/18S PCR and sequencing diagnosis of infectious endocarditis using automated pathogen enrichment and DNA extraction. Poster, Infectious Diseases Diagnostics Conference, London, UK (Poster)
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Schubert S (2017) Automated microbial DNA isolation from clinical samples for routine broad-range real‐time PCR analysis and sequence identification. Oral presentation no. OS0779, ECCMID, Wien, Austria (Presentation)